Pharmacology

Hydrocodone

Suppresses cough reflex; stimulates opiate receptors in the CNS and peripherally blocks pain impulse generation. buy Hydrocodone

Pseudoephedrine

Causes vasoconstriction and subsequent shrinkage of nasal mucous membranes by alpha-adrenergic stimulation, which promotes nasal drainage.

Indications and Usage

Suppression of cough and relief of nasal congestion and other symptoms associated with the common cold, allergies, hay fever, sinusitis, and other respiratory illnesses.

Contraindications

Hypersensitivity to any component of product, or hypersensitivity or idiosyncrasy to sympathomimetic amines which may be manifested by insomnia, dizziness, weakness, tremor, or arrhythmias. Patients known to be hypersensitive to other sympathomimetic amines may exhibit cross sensitivity with pseudoephedrine. Sympathomimetic amines are contraindicated in patients with severe hypertension, severe coronary artery disease, and patients on MAOI therapy. P-V-Tussin tablets are contraindicated in breast-feeding mothers because of the higher than usual risk for infants from sympathomimetic amines. buy Hydrocodone

Dosage and Administration

Maximum dose
Adults

Hydrocodone 20 mg/day; pseudoephedrine 240 mg/day.

Adults

For specific dosing by product, refer to the individual manufacturer's prescribing information.

Cough and nasal congestion Liquid Usual dosage

5 mL (3 to 5 mg hydrocodone) to 10 mL (6 mg hydrocodone) 4 times daily as needed.

Maximum dosage

Hydrocodone 20 mg/day; pseudoephedrine 240 mg/day.

Tablets Usual dosage

1 tablet every 4 to 6 h as needed.

Maximum dosage

Hydrocodone 20 mg/day; pseudoephedrine 240 mg/day (4 tablets/day). buy Hydrocodone